All Bets Are On: Expert NFL Week 1 Betting Picks & Predictions

NFL Week One is officially here, so ESPN Cleveland's Bruce Drennan and Matt Fontana submitted their top bet picks for the first week of pro football action. 

Let's take a look at the bets they like this week.

Cleveland Browns @ Kansas City Chiefs

Both Fontana and Drennan are taking the Browns +6.5. While this is going to be a close game against an impressive opponent in a loud environment, both Fontana and Drennan believe the Cleveland Browns keep this game with Kansas City close.

Arizona Cardinals @ Tennessee Titans

Arguably one of the tougher matchups to predict this week, Fontana and Drennan were conflicted in their opinions. The Tians are three-point favorites at home, making this game a virtual toss-up in the eyes of the oddsmakers.

 Fontana took the Cardinals +3, while Drennan took the Titans -3.

Los Angeles Chargers @ Washington Football Team

Both Fontana and Drennan took the Chargers on the road +1.

Seattle Seahawks @ Indianapolis Colts

Both Fontana and Drennan took the Seahawks -3 at home.

Pittsburgh Steelers @ Buffalo Bills

Fontana and Drennan were conflicted with this pick. Fontana took the Bills -6.5 while Drennan believes the Steelers can cover the 6.5 point spread and keep this a much closer game.

Green Bay Packers vs. New Orleans Saints

This game will actually take place in Florida, as the New Orleans community works through the situation with Hurricane Ida. Drennan took the underdog Saints +3.5 for Jameis Winston's debut as the starting QB, while Fontana took the Packers -3.5.

Chicago Bears @ Los Angeles Rams

On Sunday Night Football, despite the big spread, Fontana and Drennan agreed to take the Rams -7.5 over Andy Dalton's Chicago Bears.

Baltimore Ravens @ Las Vegas Raiders

A Monday Night Football matchup, Fontana and Drennan were conflicting with this bet. Fontana took the Ravens -4.5 on the road while Drennan took Jon Gruden's Raiders +4.5 at home.