Detroit Pistons @ Orlando Magic (7 p.m.)

Favored Team and Spread: ORL -2.5

Total Points: 212.5

Two of the worst teams in the Eastern Conference square off here as the Pistons and the Magic face off. Detroit is 2-0 this season against the Magic but are on a three-game skid. Orlando has been struggling as well, as they are 3-18 at Amway Center this season.

Cade Cunningham is coming off a 34 points, eight rebounds, eight assists, four blocks, and two steals performance against the Denver Nuggets and looks to have finally found his stride.

The Pistons are 7-2 Against The Spread in their last nine games against the Magic so go with them to cover as well as the under.

Boston Celtics @ Atlanta Hawks (7 p.m.)

Favored Team and Spread: ATL -2

Total Points: 218

The Atlanta Hawks have been able to score the ball effectively this season behind point guard Trae Young's incredible season as he is top five in points (27.7) and assists (9.3) as the Hawks are seventh in the NBA, scoring 111.4 points per game.

Compare that to Boston, who is 19th in scoring with 108 points per game and will need small forward Jayson Tatum to continue dominating lately.

The Hawks are 1-0 this season against the Celtics, and this could be an important matchup in the Eastern Conference come playoff time. The Celtics are 1-4 Against The Spread in their last five games against the Hawks, so I will lay the two points and go with the Atlanta Hawks.

The over is 11-5-1 in their last 17 games against each other so go with over 218 points as well.

Los Angeles Lakers @ Charlotte Hornets (7:30 p.m., ESPN)

Favored Team and Spread: CHA -7

Total Points: 227.5

The Lakers are on the second half of a back-to-back and three games in four days during the East Coast trip as they take on the Hornets. LeBron James sat out on Thursday due to a sore left knee, but I expect him to play here.

Small forward Kelly Oubre Jr (ankle) is questionable, while small forward Gordon Hayward (foot) is ruled out.

Charlotte is leading the NBA with 114.9 points per game, and this Lakers team is the fifth-worst defense, so points should be flying onto the scoreboard.

Go with the Hornets to cover the spread at home and the over to hit.

Denver Nuggets @ New Orleans Pelicans (8 p.m.)

Favored Team and Spread: DEN -6

Total Points: 215.5

The Nuggets have been playing incredibly well offensively as of late as in their last five games, they are scoring 119.8 points and are 4-1 in that stretch. The Pelicans are averaging 104.5 points in their last four games but are just 2-2 in those games.

Small forward Brandon Ingram (ankle) is doubtful, and shooting guard Josh Hart (ankle) is questionable. Center Nikola Jokic has been feasting as of late as in his last five games; he is averaging 32.6 points, 13 rebounds, 9.4 assists, 0.6 blocks, and 1.8 steals.

However, Denver is a brutal 0-5-1 ATS in their last six games, so go with New Orleans to cover and the under to hit.

Los Angeles Clippers @ Miami Heat (8 p.m.)

Favored Team and Spread: MIA -6.5

Total Points: 210.5

In one of the more interesting games on the slate, the Clippers will take on the top team in the East in the Heat.

Point guard Kyle Lowy (personal) is out, but power forward Jimmy Butler (toe) is questionable for this game. Remember that power forward Marcus Morris Sr (personal), small forward Paul George (elbow), and small forward Kawhi Leonard (knee) are all out for Los Angeles as well here.

Miami is the fourth-best defensive team as they are holding their opponents to 103.9 points per game this season and should have no issue doing it here.

The Heat have covered in their last four home games, so they should do so again, and the under should hit as I see a slower-paced game in here with a bunch of injuries on both sides of the court.

Portland Trail Blazers @ Houston Rockets (8 p.m.)

Favored Team and Spread: POR -2.5

Total Points: 232.5

Portland has been decimated by injuries as they are now without small forward Nassir Little (shoulder), power forward Cody Zeller (knee), small forward Larry Nance Jr (knee), and point guard Damian Lillard (abdominal).

The CJ McCollum show isn't going to get it done against most teams as a solo act, though. However, the Rockets are last in the Western Conference and have struggled at home.

These are two of the four worst defenses in terms of points per game allowed in the NBA, so go with the OVER, and Portland should cover as they have the better roster, even with the injuries surrounding them.

Utah Jazz @ Memphis Grizzlies (8 p.m.)

Favored Team and Spread: MEM -4

Total Points: 225.5

Utah has lost each of their previous three games, and it doesn't look like it will be getting any better right now.

Donovan Mitchell (concussion) and Rudy Gobert (calf) are still expected to both be out, and that is a huge blow to them as they continue to struggle without their two best players. Memphis has point guard Ja Morant coming off 41 points, five rebounds, eight assists, and two steals in 37 minutes against the Spurs last game, and he looks like one of the next elite guards in the sport.

The under is 31-11 in their last 42 games in Memphis, so take the under as well as Memphis -4 as they have been dominating and can't keep up with Morant's ability to score the basketball right now.

Indiana Pacers @ Oklahoma City Thunder (8 p.m.)

Favored Team and Spread: OKC -1

Total Points: 216

Indiana is depleted with injuries as power forward Domantas Sabonis (ankle), point guard TJ McConnell (wrist), center Myles Turner (foot), small forward TJ Warren (foot), and shooting guard Malcolm Brogdon (Achilles) are all out for this game.

The Thunder are a feisty team, and the Pacers have been disappointing on the road with a miserable 5-19 road record this season. Point guard Shai Gilgeous-Alexander has scored at least 29 points in four of his last five games, and the combination of him and rookie shooting guard Josh Giddey have been showing signs of being a productive duo in the league for years to come.

Go with the Thunder to cover the spread and the under to hit as it hit in seven of the previous nine games against one another, and Indiana is going to struggle finding points.

Chicago Bulls @ San Antonio Spurs (8:30 p.m.)

Favored Team and Spread: CHI -2

Total Points: 228.5

The Chicago Bulls are the more talented team in this matchup despite the injuries that are mounting up. Chicago will be without small forward Derrick Jones Jr (knee), shooting guard Alex Caruso (wrist), point guard Lonzo Ball (knee), and small forward Patrick Williams (wrist) for another month or so.

However, the combination of Nikola Vucevic and Zach LaVine should be able to handle the Spurs. Chicago is one of the best shooting teams as they are second in the league, shooting 47.4 percent from the floor.

San Antonio has failed to cover in their last six games as an underdog so go with the Bulls -2 as well as the under as that is too many implied points for both sides.

Minnesota Timberwolves @ Phoenix Suns (9 p.m.)

Favored Team and Spread: PHO -9.5

Total Points: 231.5

Karl-Anthony Towns had a game as he had 23 points by halftime against the Golden State Warriors last night and should have no issue dominating again against a team without much size.

Center DeAndre Ayton (ankle), center Javale McGee (knee), point guard Cameron Payne (wrist), and small forward Jae Crowder (wrist) are leading the inactive list for the Suns. That is too much size and production missing to be able to win by double digits, so go with the Timberwolves to cover on the second half of a back-to-back.

This number feels too high, and the under has hit in 10 of the previous 14 meetings in Phoenix, so under 231.5 points feels right. Also, remember that these teams are both top 10 in points per game allowed this season.

New York Knicks @ Milwaukee Bucks (10 p.m., ESPN)

Favored Team and Spread: MIL -9

Total Points: 215.5

There is no reason why this game should be as late as it is, but the New York Knicks will travel to take on the Milwaukee Bucks. Milwaukee is leading the season series 2-1, and this is the final regular-season matchup between these teams.

Giannis has been red hot in his last three games as he is averaging 29.7 points, 12 rebounds, 4.3 assists, one block, and 1.3 steals.

Go with the Bucks to cover the spread as they are 8-3 ATS in the last 11 games against the Knicks and the under as it hit in the last four meetings.

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NBA Daily Betting Guide: NBA Best Bets for January 28, 2022